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Chelation

Question: What is Chelation?

Answer: Complex formation involving a metal ion and two or more polar groupings of a single molecule; thus, in heme, the Fe2+ ion is chelated by the porphyrin ring. Chelation can be used to remove an ion from participation in biological reactions, as in the chelation of Ca2+ of blood by EDTA, which thus acts as an anticoagulant.

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