Folate

Why is Folate important for your Healthspan?

‍Folate levels are fundamental for maintaining cellular health and supporting a long Healthspan. This vitamin plays a key role in DNA synthesis and repair, which is important for preventing cellular damage and promoting proper cell division throughout the body. Adequate folate also contributes to healthy red blood cell formation and is involved in metabolic pathways that affect cardiovascular and brain health. Insufficient folate can lead to anemia, fatigue, and may impact cognitive function, thereby affecting overall vitality and long-term well-being.

‍What is Folate?

Folate is a naturally occurring water-soluble B vitamin, also known as Vitamin B9. The term 'folate' refers to the various forms found naturally in foods, while 'folic acid' is the synthetic form often used in fortified foods and dietary supplements. This essential nutrient plays a crucial role in numerous bodily functions. It is vital for DNA synthesis and repair, which underpins proper cell growth and division. Folate is also indispensable for the production of red blood cells in the bone marrow and participates in the metabolism of amino acids, including homocysteine, where it helps convert it into other substances. Its involvement in these fundamental cellular processes makes it important for overall physiological function, especially for rapidly dividing cells.

‍How do we take action?

To maintain healthy folate levels, one should ensure a diet rich in natural folate sources, such as leafy green vegetables, legumes, asparagus, and fortified grains. If dietary intake is insufficient or absorption is a concern, a healthcare provider may recommend supplementation, particularly for individuals with specific needs, such as those planning pregnancy. It is also important to address any underlying conditions that might impair folate absorption. Regular monitoring of folate levels can help ensure optimal nutritional status and support overall Healthspan.

‍Additional Sources

1. Medici, V., & Halsted, C. H. (2013). Folate, alcohol, and liver disease. Molecular Nutrition & Food Research, 57(4), 596–606. https://doi.org/https://doi.org/10.1002/mnfr.201200077

2. Mikkelsen, K., & Apostolopoulos, V. (2019). Vitamin B12, Folic Acid, and the Immune System. In M. Mahmoudi & N. Rezaei (Eds.), Nutrition and Immunity (pp. 103–114). Springer International Publishing. https://doi.org/10.1007/978-3-030-16073-9_6

3. Allen, L. H. (2008). Causes of Vitamin B12 and Folate Deficiency. Food and Nutrition Bulletin, 29(2_suppl1), S20–S34. https://doi.org/10.1177/15648265080292S105

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