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High Density Lipoprotein Cholesterol (HDL)

Heart Health
Published:
December 5, 2025

Author: MyHealthspan Team

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High Density Lipoprotein Cholesterol (HDL)

Why is HDL Cholesterol important for your Healthspan?

HDL Cholesterol levels are important for cardiovascular health. This type of cholesterol plays a role in removing excess cholesterol from arterial walls and transporting it back to the liver for excretion. This process can help prevent the accumulation of plaque in arteries, which is linked to heart disease and stroke. Maintaining healthy HDL levels contributes to a well-functioning circulatory system, supporting long-term vitality and reducing the risk of serious cardiac events.

What is HDL Cholesterol?

High-Density Lipoprotein (HDL) Cholesterol is one of the main types of lipoproteins, which are particles that transport cholesterol and fats through the bloodstream. HDL is often referred to as 'good cholesterol' because of its unique role in what is called 'reverse cholesterol transport.' In this process, HDL particles collect excess cholesterol from cells and arterial walls and carry it back to the liver. Once in the liver, this cholesterol can then be processed and eliminated from the body. This function helps to prevent the buildup of cholesterol-rich plaques (atherosclerosis) within the arteries, which can narrow blood vessels and impede blood flow.

How do we take action?

To optimize HDL Cholesterol levels, one should focus on lifestyle modifications. Regular aerobic exercise is particularly effective at raising HDL. Adopting a balanced diet that emphasizes healthy fats (found in olive oil, avocados, nuts, and fatty fish) while limiting trans fats and excessive refined carbohydrates can also be beneficial. Maintaining a healthy body weight and avoiding smoking are further important steps. For some individuals, certain medications might also influence HDL levels. Consistent healthy habits are key to supporting optimal HDL Cholesterol and overall cardiovascular Healthspan.

Additional Sources

1. Lund-Katz, Sissel and Phillips, Michael. High Density Lipoprotein Structure–Function and Role in Reverse Cholesterol Transport. Subcell Biochem. 2010; 51: 183–227. doi: 10.1007/978-90-481-8622-8_7

2. Major Lipids, Apolipoproteins, and Risk of Vascular Disease. JAMA. 2009;302(18):1993-2000. doi:10.1001/jama.2009.1619

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https://www.myhealthspan.com/articles/hdl-high-density-lipoprotein-cholesterol