Why are Neutrophils important for your Healthspan?
Neutrophil levels are important for maintaining your body's immediate defense against infections. As the primary white blood cells to arrive at sites of infection or injury, they play a crucial role in combating bacteria and fungi. Imbalances in neutrophil counts, such as consistently high levels, can indicate ongoing infection or inflammation, while very low levels can increase susceptibility to illness. Maintaining balanced neutrophil numbers supports a healthy immune response and overall resilience against acute challenges, contributing to sustained well-being.
What are Neutrophils?
Neutrophils are the most abundant type of white blood cell (leukocyte), making up a significant portion of your body's immune cells. They are a core component of the innate immune system, meaning they provide a rapid, non-specific response to invading pathogens. Neutrophils are typically the first immune cells to arrive at a site of infection or inflammation, where they actively engulf and destroy microorganisms, a process known as phagocytosis. They also release various antimicrobial substances to neutralize threats. Their short lifespan and high turnover mean that the bone marrow constantly produces new neutrophils to maintain a robust defense system.
How do we take action?
If neutrophil levels are found to be outside the typical range, one should consult with a healthcare provider to investigate potential underlying causes. Elevated neutrophils most commonly suggest a bacterial infection or significant inflammation, but can also be influenced by stress or certain medications. Low neutrophil levels (neutropenia) can increase vulnerability to infections and might stem from viral infections, bone marrow issues, or side effects from specific treatments. Strategies involve addressing the diagnosed underlying condition, supporting overall immune health through a balanced diet, adequate sleep, and effective stress management, which helps maintain appropriate immune cell balance for a strong Healthspan.
Additional Sources
Kruger, P., Saffarzadeh, M., Weber, A. N., Rieber, N., Radsak, M., von Bernuth, H., Benarafa, C., Roos, D., Skokowa, J., & Hartl, D. (2015). Neutrophils: Between host defence, immune modulation, and tissue injury. PLoS pathogens, 11(3), e1004651. https://doi.org/10.1371/journal.ppat.1004651
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