Triglyceride-Glucose (TyG) Index

Why is the Triglyceride-Glucose Index important for your Healthspan?

‍The Triglyceride-Glucose Index is an important marker for long-term metabolic health. Insulin resistance is a key underlying factor for numerous chronic conditions, including type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver disease. A high index suggests a state of insulin resistance that, if left unaddressed, can impact long-term vitality and increase disease risk. Monitoring this index provides a simple, accessible way to assess metabolic function and guide strategies to improve insulin sensitivity.

‍What is the Triglyceride-Glucose Index?

The Triglyceride-Glucose Index (TyG index) is a calculated value derived from your fasting blood glucose and fasting triglycerides. It is used as an easy-to-obtain surrogate marker for insulin resistance, a condition where the body’s cells do not respond effectively to the hormone insulin. When this occurs, both blood sugar and triglycerides can rise. The index is typically calculated using the formula: ln[fasting triglycerides (mg/dL) × fasting glucose (mg/dL)] / 2. This combined metric is considered a more effective indicator of insulin resistance than either triglycerides or glucose alone, and it has been shown in research to be comparable to more complex and expensive methods for measuring insulin resistance.

‍How do we take action?

If the Triglyceride-Glucose Index is elevated, one should focus on lifestyle modifications to improve insulin sensitivity. The most effective strategies include regular physical activity, particularly a combination of aerobic and resistance training, and adopting a balanced diet that limits refined carbohydrates, sugars, and unhealthy fats. Maintaining a healthy body weight and managing stress effectively can also help. These actions can improve your body’s response to insulin, which helps support long-term metabolic health and overall Healthspan."

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