Nutrients
Folate (vitamin B9)
Folic acid, vitamin B9
Included in Baseline and Complete.
Compare membershipsNew cells and healthy blood depend on folate.
Folate is a B vitamin your body uses to make DNA and new cells, including red blood cells. Folic acid is the form added to fortified foods and supplements.
Folate can reflect your recent meals.
Folate in serum mostly reflects recent intake, while folate in red blood cells reflects intake over weeks to months. A recent meal or supplement can raise a serum result, which is why you may be asked to fast first.
Canada has required folic acid in certain grain products since 1998. Low folate can still occur with a limited diet, heavy alcohol use, absorption problems such as celiac disease, and some medicines, including methotrexate and certain anti-seizure drugs.
Folate and B12 work as a team, so they're best read together.
Questions
Why are folate and B12 often tested together?
Both are needed to make healthy red blood cells, and a shortage of either can cause a similar type of anemia. High folic acid intake can correct the anemia of B12 deficiency while nerve effects continue, so checking both helps avoid missing a B12 problem.
Does folate matter if I'm planning a pregnancy?
Yes. Getting enough folic acid before and during early pregnancy helps lower the risk of neural tube defects such as spina bifida. A clinician can advise on the right amount for you.