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Immune and inflammation

Monocytes (absolute monocyte count)

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Your immune system's cleanup crew.

Monocytes are large white blood cells that travel through your blood and then move into tissues, where they become macrophages and dendritic cells. They clear away germs and damaged cells and help coordinate the wider immune response.


A higher count can point to ongoing immune activity.

Monocytes can rise with infections, including longer-lasting ones, and with autoimmune and inflammatory conditions such as lupus. Less commonly, a persistently high count points to a blood condition that needs specialist review.

Monocytes also take part in the plaque buildup inside arteries, and researchers are studying their role in heart disease. For now, the monocyte count isn't used on its own to judge cardiovascular risk.

Questions

What does a low monocyte count mean?

A low count is less common. Chemotherapy, some other medications, and bone marrow conditions can lower it. A clinician reads it in light of your other white cell results.

Is a slightly high result a concern?

A small rise on one test, especially after a recent illness, is usually read in context and may be rechecked later. A clinician looks at whether it persists and how it fits with the rest of your blood count.

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