Heart and cholesterol

LDL cholesterol

LDL-C, low-density lipoprotein cholesterol

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Most cholesterol guidance starts with LDL.

LDL cholesterol measures the cholesterol carried by low-density lipoproteins, particles that can deposit cholesterol in artery walls over time. It's one of the main results clinicians use to assess cardiovascular risk and guide treatment decisions.

LDL particles can become trapped in artery walls.

LDL particles carry cholesterol from the liver to the cells that need it. The more of these particles there are in your blood, the more likely some are to become trapped in artery walls, where they contribute to plaque.

Many labs calculate LDL cholesterol from your total cholesterol, HDL, and triglycerides. When triglycerides are high, Canadian guidelines prefer non-HDL cholesterol or ApoB, which give a more reliable picture of risk.

Questions

What can raise LDL cholesterol?

Genes play a large role, and some families have inherited high LDL. Eating patterns high in saturated fat, carrying extra weight, and getting older can also raise it. Some medications and medical conditions can affect it too.

Is a result within the lab's reference range always fine?

It isn't always. The right level for you depends on your overall cardiovascular risk, including your age, blood pressure, smoking, diabetes, kidney health, and family history. A clinician can help you understand what your result means for you.

What happens if my LDL is high?

Your result is read with your other cholesterol results and your overall risk. 1:1 longevity coaching can help you decide on next steps, and your own clinician can talk through whether medication makes sense for you.

Sources and references